Getting to Pakistan is possible in several ways, from overland travel to airport entry. Be warned, though, that there are certain political and legal matters that could affect the ease with which you get into the country. For example, an Israeli national may well find it impossible to enter Pakistan just because of the ongoing tensions between the two countries, which dictate that an Israeli passport be invalid in Pakistan. That said, there are nuances to such matters that are best clarified too, including the fact that a person travelling to Pakistan who just so happens to have either an Israeli visa or stamp on his passport (but is not an Israeli national himself) is usually not prevented from entering the country.
These are things that one needs to investigate when thinking about going to another country, so it is best to check with the appropriate bureau in your area what may affect your plans ahead of time. Take note too that it is best to assume that you are required to apply for a visa in advance, given that there are only a few countries whose nationals are permitted visas upon arriving in Pakistan.
As for the actual journey, you can take any of several routes, as was mentioned earlier. Possibly the easiest is that of getting to Pakistan by air. Pakistan is actually fairly well-set-up when it comes to its air travel, having already amassed a total of 148 airports by 2010. The most important ones for international travellers are the bigger airports in the large cities, of course. The Benazir Bhutto International Airport in the capital, for instance, is among the busiest airports in the country. Other major airports may be found in the well-known cities of Lahore and Karachi, and if you do end up choosing to fly to Pakistan, the chances are high that you shall be ending up in one of these cities at the end of the flight.
If air travel is not your thing, however, you may still opt to take the overland routes instead. It is worthwhile to note that several of the overland options may be more dangerous than others. Taking the trains that connect the country to its neighbours like Iran and India, for instance, could be less than ideal for your security, given that getting to Pakistan on land this way has long been associated with getting attacked by regional militants or terrorists in transit. The trains are neither fast nor timely, so it would really be ill-advised to rely on them for your travel needs.
The better options for those thinking of getting to Pakistan overland are of car rental and bus transit. The former is only advisable if you are willing to take the longer journey in exchange for better views and if you are taking the Silk Road. It becomes inadvisable if you are trying to enter the country from Afghanistan, given how dangerous the roads between the two countries are and how unpredictable the military at the borders can be. Bus is probably better for most people, though, and both China and India have bus lines that make the trip expressly from the border towns of Kashgar and Delhi to cross over into Pakistan.